Microsoft Outlook and Adobe PDF have been the bane of my existence these past few days.

What does "bane of my existence" mean, anyway?

Well, according to MerriamWebster, "bane" is "a source of harm or ruin".
So, "bane of my existence" is "a source of harm or ruin of my existence".

Yeah, that about covers what Outlook and PDF files have been doing to me today!